Toxicity of methyldopa (Aldomet) to mouse neuroblastoma cells in vivo.
نویسندگان
چکیده
The adrenergic blocking agent methyldopa (Aldomet) is toxic to C-1300 neuroblastoma cells in vivo. Four injections of Aldomet at a dose of 7.5 mg/injection were given over a period of 24 hr to C-1300 neuroblastoma-bearing mice. This treatment killed a significant proportion of the C-1300 neuroblastoma cells. Flow cytometric data suggest that sensitivity of tumor cells to Aldomet is not related to the cell cycle.
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ورودعنوان ژورنال:
- Cancer research
دوره 43 8 شماره
صفحات -
تاریخ انتشار 1983